Why the study?
Does lumbar epidural anesthesia with bupivacaine alter baroreflex control of heart rate compared to saline in unpremedicated patients?
Population
12 unpremedicated patients
Comparison
8 ml of 0.5% plain bupivacaine in the epidural… vs 8 ml of saline at the same level in the epidural…
Design
Other
Authors
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May enhance vagal tone via reduced venous return; leaves open clinical relevance pending larger trials.
Does lumbar epidural anesthesia with bupivacaine alter baroreflex control of heart rate compared to saline in unpremedicated patients?
Lumbar epidural anesthesia enhances cardiac vagal tone and baroreflex sensitivity primarily through a decrease in venous return.
Baron et al. (1986) studied this question.
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