Population
In vitro working hearts of the turtle, Chrysemys picta bellii, paced at 30 beats/min
Comparison
Varying input pressures under different… vs Different perfusion conditions and input…
Design
Preclinical
Authors
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Hypothesis-generating for anoxia-acidosis synergy in ischemia-tolerant hearts; leaves open translation to mammalian energetics and clinical ischemia.
This preclinical study demonstrates that anoxia and acidosis synergistically depress cardiac function in turtle hearts, while energy turnover appears independent of input pressure changes.
Jackson et al. (1995) studied this question.
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