Why the study?
Does baseline pulmonary hypertension increase the risk of death and heart failure in patients with degenerative mitral regurgitation due to flail leaflets?
Does baseline pulmonary hypertension increase the risk of death and heart failure in patients with degenerative mitral regurgitation due to flail leaflets?
In patients with degenerative mitral regurgitation due to flail leaflets, pulmonary hypertension is present in 23% of cases and independently doubles the risk of death and heart failure, supporting the consideration of mitral surgery before pulmonary hypertension is established.
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Pulmonary hypertension doubles mortality risk in flail mitral regurgitation; extends observational evidence but leaves optimal surgical timing open for prospective trials.
Barbieri et al. (2010) studied this question.
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