Population
4,168 cerebrospinal fluid specimens collected from hospitalized individuals between 2005 and 2010 in Edinburgh
Design
Cross-sectional
Follow-up
5 years (2005-2010)
Authors
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Supports HPeV3 PCR in neonatal CNS cases; cross-sectional data leaves clinical impact and screening benefit open.
HPeV3 is a highly prevalent picornavirus in CNS-related infections among very young children, highlighting the need for specific PCR screening in neonatal sepsis and meningitis cases.
Harvala et al. (2011) studied this question.
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