During an echovirus 11 outbreak, human IgG antibodies target the VP 1 protein, while IgM antibodies target VP 1, VP 2, and VP 3.
May guide VP1-based IgG serology in echovirus outbreaks; leaves open diagnostic and protective utility pending validation.
The immunoglobulin M and G specific immune response of humans to echovirus 11 proteins during an echovirus 11 outbreak was studied by the immunoblot technique. Whereas immunoglobulin G antibodies were directed most exclusively to the VP 1 protein, the immunoglobulin M antibodies were directed against VP 1, VP 2, and VP 3.
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Reigel et al. (1984) studied this question.
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