Why the study?
Does ephedrine compared to etilefrine affect systemic vascular resistance differently in patients with hypotension during combined epidural and general anesthesia?
Population
40 patients scheduled for elective abdominal surgery who developed hypotension
Comparison
Ephedrine 10 mg intravenous bolus injection vs Etilefrine 2 mg intravenous bolus injection
Design
RCT, randomized
Follow-up
5 minutes
Authors
Loading...
Etilefrine may warrant caution versus ephedrine for anesthesia hypotension; extends RCT data on vasopressor SVR effects.
Does ephedrine compared to etilefrine affect systemic vascular resistance differently in patients with hypotension during combined epidural and general anesthesia?
Etilefrine induces a more pronounced transient decrease in systemic vascular resistance than ephedrine immediately after bolus injection for anesthesia-induced hypotension.
Wajima et al. (2018) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: