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August 13, 2026Scientific ReportsOpen Access

Efficacy and safety of a topical dihydromyricetin-containing serum for facial and neck rejuvenation: a prospective clinical study

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Overview

Prospective trial evaluates safety and efficacy of dihydromyricetin serum for improving skin in individuals with photoaging, suggesting positive outcomes.

Key Points

  • To evaluate the efficacy and safety of a topical dihydromyricetin-containing serum for rejuvenating facial and neck skin afflicted by photoaging.
  • Single-arm clinical study with 30 participants aged 30–45 years
  • Topical application of DHM serum twice daily for 8 weeks
  • Clinical assessments at baseline, 4, 8, and 12 weeks using various bioengineering instruments.
  • Significant improvements in skin elasticity parameters observed at week 8 (p < 0.05)
  • Skin radiance showed significant increase at week 8, maintained through week 12
  • Reductions in infraorbital skin roughness, pore area, and redness were demonstrated.

Cite This Study

A 2026 study studied this question.

synapsesocial.com/papers/6a7d76062b0e0cff3f63f0cfhttps://doi.org/10.1038/s41598-026-65954-y
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