Population
Smooth muscle cells of 4th order arterioles in mouse skeletal muscle
Comparison
Application of channel blockers and varying… vs Baseline or control conditions without…
Design
Preclinical
Authors
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Does not support clinical translation; extends animal-model characterization of Na+ and Ca2+ channel roles in arteriolar depolarization.
This preclinical study demonstrates that both voltage-gated Na+ channels and multiple types of Ca2+ channels (T- and L-type) are involved in the depolarization of skeletal muscle arteriole smooth muscle cells.
Ulyanova et al. (2018) studied this question.
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