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August 10, 2009Acta Paediatrica

Intrabdominal fat is related to metabolic risk factors in Hispanic Americans, African Americans and in girls

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Why the study?

How do individual adipose depots associate with cardiometabolic outcomes across different races/ethnicities and genders in early pubertal children?

Population

320 early pubertal children aged 7-12 years, self-identified as African American, European American, or…

Design

Cross-sectional

Authors

KCK. CasazzaUniversity at Buffalo, State University of New YorkBGBA GowerJFJR Fernandez

Discussion

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Implication

Differential visceral fat effects by ethnicity and sex may inform pediatric risk assessment; leaves open causal mechanisms and intervention targets.

Structured PICO

How do individual adipose depots associate with cardiometabolic outcomes across different races/ethnicities and genders in early pubertal children?

P
Population
320 early pubertal children aged 7-12 years (53% male), self-identified as African American (n=114), European American (n=120), or Hispanic American (n=86).
O
Outcome
Cardiometabolic outcomes including insulin sensitivity index, blood pressure, and fasting insulinsurrogate

Intra-abdominal fat accumulation has a differential, more adverse impact on cardiometabolic risk factors in African American and Hispanic American children, as well as in girls, compared to European Americans.

Cite This Study

Casazza et al. (2009) studied this question.

synapsesocial.com/papers/6a7d84ec0631e052c4b8692fhttps://doi.org/10.1111/j.1651-2227.2009.01474.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Point: Visceral Adiposity Is Causally Related to Insulin Resistance2005 · 331 citations
  2. 2Target Value of Intraabdominal Fat Area for Improving Coronary Heart Disease Risk Factors2004 · 33 citations
  3. 3INTRA-ABDOMINAL ADIPOSE TISSUE CUT-POINTS RELATED TO ELEVATED CARDIOVASCULAR RISK IN WOMEN.1995 · 54 citations
  4. 4Deterioration of insulin sensitivity and beta-cell function in overweight Hispanic children during pubertal transition: A longitudinal assessment2006 · 50 citations
  5. 5Critical evaluation of the combined model approach for estimation of prehepatic insulin secretion1998 · 36 citations