This 1952 case report documents an instance of malignant hypertension secondary to renal ischemia.
May prompt renovascular evaluation in malignant hypertension; leaves open whether this association persists in modern cohorts.
Case Reports1 July 1952A CASE OF MALIGNANT HYPERTENSION SECONDARY TO RENAL ISCHEMIAWILLIAM H. BLAHD, M.D., RAYMOND MARCUS, M.D., DAVID M. WASSERMAN, M.D.WILLIAM H. BLAHD, M.D., RAYMOND MARCUS, M.D., DAVID M. WASSERMAN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-1-179 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere have been few reports of severe hypertension secondary to renal ischemia in which the ischemic kidney remained viable long enough to induce, by the elaboration of a pressor substance, generalized pathologic changes.1, 2In 1934, Goldblatt published the first account of experimentally produced hypertension in dogs secondary to renal ischemia.3Since that time, search for corroboration of this phenomenon in the human has not been entirely successful. There have been occasional reports of complete renal artery occlusion with associated hypertension of equivocal magnitude and duration.4-7In most of these cases, however, interruption of the renal blood supply was closely...Bibliography1. Stewart CF: Arteriosclerosis of the renal artery orifices with severe hypertension, J. A. M. A. 114: 2099-2101, 1940. Google Scholar2. LeadbetterBurkland WFCE: Hypertension in unilateral renal disease, J. Urol. 39: 611-626, 1939. CrossrefGoogle Scholar3. GoldblattLynchHanzalSummerville HJRFWW: Studies on experimental hypertension: production of persistent elevation of systolic blood pressure by means of renal ischemia, J. Exper. Med. 59: 347-379, 1934. CrossrefMedlineGoogle Scholar4. Bumpus HC: Renal infarction, case of renal hypertension, J. Urol. 52: 295-299, 1944. CrossrefGoogle Scholar5. SheaSchwartzKobilak JDJWRE: Thrombosis of left renal artery with hypertension, J. Urol. 59: 302-306, 1948. CrossrefMedlineGoogle Scholar6. Fishberg AM: Hypertension due to renal embolism, J. A. M. A. 119: 551-553, 1942. CrossrefGoogle Scholar7. Ben-Asher S: Hypertension caused by renal infarction, Ann. Int. Med. 23: 431-436, 1945. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication November 27, 1950.From the Medical Service, Wadsworth Hospital, Veterans Administration Center, and the Department of Medicine, Los Angeles, California. Sponsored by the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions of the authors are the result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe treatment of hypertensionRenal Artery Changes in HypertensionAntihypertensive AgentsHypertonieHypertonieADDENDUMTHE DIAGNOSTIC APPROACH TO HYPERTENSION DUE TO UNILATERAL KIDNEY DISEASE*†ALBERT A. BRUST, EUGENE B. FERRIS, F.A.C.P.Diagnosis of Hypertension Due to Occlusions of the Renal ArteryOcclusion of a Renal Artery as a Cause of HypertensionMALIGNANT HYPERTENSION ASSOCIATED WITH UNILATERAL RENAL ARTERY OCCLUSION: THREE CASES*EUGENE G. LAFORET, M.D. 1 July 1952Volume 37, Issue 1Page: 179-185KeywordsBloodHospital medicineHypertensionKidneysMedical servicesRenal arteriesRenal ischemiaResearch laboratoriesSecondary hypertension ePublished: 1 December 2008 Issue Published: 1 July 1952 PDF downloadLoading ...
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