Key result
The mechanisms underlying the relationship between kidney disease and hypertension remain undisclosed, with opinions over the last 25 years ranging from complete attribution to total denial.
Design
Review
Authors
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Persistent uncertainty on kidney-hypertension mechanisms warrants caution against causal assumptions; leaves open mechanistic research to resolve bidirectional links.
A historical review discussing the mechanisms, diagnosis, and treatment of hypertension of renal vascular origin.
Page et al. (1959) conducted a review in Hypertension of renal vascular origin. The mechanisms underlying the relationship between kidney disease and hypertension remain undisclosed, with opinions over the last 25 years ranging from complete attribution to total denial.
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