Key result
This review examines existing clinical studies on remote ischemic preconditioning in vascular surgery, highlighting design optimization and challenges following recent major trials.
Why the study?
Does remote ischemic preconditioning provide organ protection in patients undergoing vascular surgery?
Does remote ischemic preconditioning provide organ protection in patients undergoing vascular surgery?
This review highlights the current evidence, design optimization, and challenges of remote ischemic preconditioning in vascular surgery following recent major trials.
Answers are grounded in this paper and cite their sources.
Routine remote ischemic preconditioning should not yet change practice for vascular surgery; leaves open the need for optimized.
Remote ischemic preconditioning (RIPC) is a theoretically attractive strategy for organ protection; and phase 2 studies in a variety of settings have yielded promising results. In this article, we review the existing clinical studies on RIPC in vascular surgery. We examine aspects of design that may potentially be optimized in future vascular surgery studies and we highlight some challenges that have emerged since the publication of the Remote Ischaemic Preconditioning for Heart Surgery (RIPHeart) trial and the Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery (ERICCA) trial.
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Healy et al. (2017) conducted a review in Vascular surgery. Remote ischemic preconditioning (RIPC) was evaluated. This review examines existing clinical studies on remote ischemic preconditioning in vascular surgery, highlighting design optimization and challenges following recent major trials.
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