Population
Synthesized peptide containing the predicted coiled-coil region of myosin 10 and recombinant myosin 10
Comparison
Structural analysis using circular dichroism… vs Myosin 5 heavy meromyosin
Design
Preclinical
Authors
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Novel myosin 10 structure extends motor protein models; leaves open functional relevance in cardiovascular cells.
The predicted coiled-coil domain of myosin 10 forms a novel elongated single alpha-helix structure rather than a traditional coiled coil, potentially increasing the size of its working stroke.
Knight et al. (2005) studied this question.
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