March 1, 1970American Journal of Epidemiology
Familial Factors in Premature Coronary Heart Disease—a Preliminary Report From the Tecumseh Community Health Study1
Why the study?
Does parental death from coronary heart disease increase the incidence of premature coronary heart disease in men?
Population
Men from the Tecumseh Community Health Study, categorized by age (younger 40-59, older 60+)
Comparison
Parental death from coronary heart disease (CHD) vs Parental death from other causes
Design
Cohort
Authors
Discussion
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Member takes
Implication
May inform family history screening for premature CHD in younger men; extends familial aggregation data but leaves open causal mechanisms and interventions.
Structured PICO
Does parental death from coronary heart disease increase the incidence of premature coronary heart disease in men?
P
Population
Men from the Tecumseh Community Health Study, categorized by age (younger 40-59, older 60+)
I
Intervention
Parental death from coronary heart disease (CHD)
C
Comparator
Parental death from other causes
O
Outcome
Incidence rates of coronary heart disease (fatal and non-fatal)hard clinical
Familial factors, specifically parental death from CHD before age 65, play an important role in the development of premature CHD in men.
Cite This Study
Deutscher et al. (1970) studied this question.