Key result
Children treated for congenital heart disease had a higher prevalence of obesity compared to healthy controls (22.7% vs 15.5%, P=.015), and overweight was associated with elevated systolic blood pressure.
Why the study?
Overweight and obesity may have a greater negative impact in children with congenital heart disease, prompting evaluation of obesity rates and systolic hypertension as an early complication.
Is the prevalence of overweight, obesity, and systolic hypertension higher in children treated for congenital heart disease compared to healthy controls?
Observational (n=440)
No
Is the prevalence of overweight, obesity, and systolic hypertension higher in children treated for congenital heart disease compared to healthy controls?
Absolute Event Rate: 35.4% vs 37.3%
p-value: p=.738
Children treated for congenital heart disease have a significantly higher prevalence of obesity compared to healthy controls, which is strongly associated with elevated systolic blood pressure.
May support obesity screening in pediatric CHD follow-up; leaves open causal links to systolic hypertension.
INTRODUCTION: The negative impact of overweight and obesity is potentially greater in children affected by a congenital heart disease (CHD). The aim of this study is to calculate the proportion of overweight and obesity in children who underwent an intervention for CHD, and to investigate systolic arterial hypertension as a possible early cardiovascular complication. PATIENTS AND METHODS: A retrospective study was conducted on patients aged 6-17 years treated for CHD, and healthy control subjects, followed-up in a Paediatric Cardiology Clinic. Body mass index percentiles were calculated according to the criteria of WHO. A review was performed on the anthropometric and clinical data, as well as the systolic blood pressure (SBP). RESULTS: A total of 440 patients were included, of which 220 had CHD. The proportion of combined obesity and overweight (body mass index percentile ≥85) was 36.4% (37.3% in healthy subjects and 35.4% in patients with CHD, P=.738). A higher prevalence of obesity (body mass index percentile ≥97) was found in CHD patients (22.7%) compared to 15.5% in healthy subjects (P=.015). SBP percentiles were higher in overweight compared to normal-weight patients (P < .001). The prevalence of SBP readings ≥ the 95th percentile was greater in overweight than in normal weight CHD patients (29.5% versus 7.7%, P < .001) and also in the overweight healthy controls compared to those of normal weight (12.2% versus 0.7%, P < .001). CONCLUSIONS: The proportion of obesity is high in children treated for CHD and it is associated with elevated SBP levels. The risk of long-term complications needs to be reduced by means of prevention and treatment of obesity in this vulnerable population.
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Perín et al. (2018) conducted an observational in Congenital heart disease (n=440). Congenital heart disease vs. Healthy control subjects was evaluated on Combined obesity and overweight (body mass index percentile ≥85) (p=.738). Children treated for congenital heart disease had a higher prevalence of obesity compared to healthy controls (22.7% vs 15.5%, P=.015), and overweight was associated with elevated systolic blood pressure.
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