Key result
Acute stress reaction-related suicide attempts were associated with significantly higher initial leukocyte counts compared to healthy controls (9.71 vs 7.48 x10^3/uL, p=0.003), with no significant difference in initial platelet counts or mean platelet volume.
Why the study?
Does acute stress reaction related to suicide attempt alter leukocyte and platelet counts compared to matched controls?
Population
63 individuals, comprising 30 patients admitted to the emergency room after a suicide attempt with acute…
Comparison
Suicide attempt with acute stress reaction (ASR) vs Controls matched for gender and age from the…
Design
Case-control
Authors
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May indicate acute inflammatory response in suicide attempts; hypothesis-generating for stress biomarkers, should not change practice.
Case-Control (n=63)
Does acute stress reaction related to suicide attempt alter leukocyte and platelet counts compared to matched controls?
Absolute Event Rate: 9.71% vs 7.48%
p-value: p=0.003
Acute stress reaction following a suicide attempt is associated with increased leukocyte counts but not platelet counts or MPV, while antidepressant use may have an antiplatelet effect.
Koçer et al. (2013) conducted a case-control in Acute stress reaction (ASR) related suicide attempt (n=63). Acute stress reaction (ASR) related suicide attempt vs. Healthy controls was evaluated on White blood cell (WBC) count at first measurement (within 3 hours of admission) (p=0.003). Acute stress reaction-related suicide attempts were associated with significantly higher initial leukocyte counts compared to healthy controls (9.71 vs 7.48 x10^3/uL, p=0.003), with no significant difference in initial platelet counts or mean platelet volume.
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