Key result
Complete resolution of pulmonary embolism on CT angiography was observed in 81% of patients after 28 days, with faster resolution in main and lobar arteries than in segmental branches.
Observational (n=69)
Yes
Most patients with acute pulmonary embolism show complete resolution on CT angiography after 28 days, with central emboli resolving faster than peripheral ones.
Should not yet change PE follow-up imaging; leaves open optimal timing and anticoagulation duration in prospective studies.
OBJECTIVE: The objective of our study was to retrospectively determine the rate of resolution of pulmonary emboli (PEs) in individual vessels and the rate of complete resolution of PEs on CT angiography. MATERIALS AND METHODS: Follow-up CT pulmonary angiograms, obtained during the period from January 2006 through May 2009, of 69 patients with acute PE from two hospitals were assessed. Initial and follow-up CT angiograms were reread together by one radiologist at both of the hospitals. Images were obtained using a 10-, 16-, 40-, or 64-MDCT angiography unit with a 0.5-mm collimation, 1.25- to 2.0-mm reconstruction, 0.3- to 0.5-second rotation time, and 7.5-mm/rotation table speed. All CT angiograms were obtained using a PE protocol. RESULTS: Follow-up CT angiograms were obtained in 35 men and 34 women who ranged in age from 17 to 92 years (mean age, 58 +/- 17 [SD] years). Complete CT angiographic resolution of PE was seen in six of 15 patients (40%) 2-7 days after diagnostic imaging. After day 28, complete resolution occurred in 17 of 21 patients (81%). The main pulmonary arteries showed complete PE resolution during days 2-7 in seven of nine patients (78%) and after day 28 in 34 of 36 (94%). The lobar pulmonary arteries showed complete resolution of PE during days 2-7 in 23 of 33 patients (70%) and after 28 days in 44 of 48 (92%). The segmental pulmonary arteries showed complete resolution during days 2-7 in eight of 21 patients (38%) and after day 28 in 38 of 38 (100%). CONCLUSION: Most patients (81%) showed complete resolution of PE on CT angiography after 28 days. PEs resolved faster in the main and lobar pulmonary arteries than in the segmental branches.
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Stein et al. (2010) conducted an observational in Acute pulmonary embolism (n=69). Follow-up time was evaluated on Complete resolution of pulmonary emboli on CT angiography after day 28. Complete resolution of pulmonary embolism on CT angiography was observed in 81% of patients after 28 days, with faster resolution in main and lobar arteries than in segmental branches.
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