Why the study?
Does Angiotensin II stimulation up-regulate specific genes related to extracellular matrix production in cultured human mesangial cells?
Does Angiotensin II stimulation up-regulate specific genes related to extracellular matrix production in cultured human mesangial cells?
AngRem104 is a novel gene up-regulated by Angiotensin II in human mesangial cells, potentially playing a role in glomerular sclerosis via fibronectin expression.
Authors
No takes yet. Share an insight, caveat, or question.
AngRem104 may mediate Ang II-driven mesangial fibrosis; leaves open its viability as a therapeutic target in hypertensive nephropathy.
Liang et al. (2003) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: