Population
Arp1p (actin-related protein 1)
Comparison
Charge-cluster-to-alanine scanning mutagenesis vs Actin mutations
Design
Preclinical
Authors
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Arp1p surface mapping refines dynactin models; leaves open in vivo roles and mammalian validation.
Alanine scanning mutagenesis of Arp1p identified a unique surface region crucial for its interaction with dynactin components Jnm1p and Nip100p.
Clark et al. (2005) studied this question.
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