December 15, 1995The Journal of Cell BiologyOpen Access

Actin filaments in yeast are unstable in the absence of capping protein or fimbrin.

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Population

Saccharomyces cerevisiae (yeast) models

Design

Preclinical

Authors

TKTatiana KarpovaNational Institutes of Health KTKelly TatchellLouisiana State University Health Sciences Center Shreveport JCJohn A. CooperNorthwestern University

Discussion

Member takes

Implication

Supports CP-mediated actin stabilization in yeast; challenges Dictyostelium observations and leaves open relevance to higher eukaryotes.

Structured PICO

Population

Saccharomyces cerevisiae (yeast) models

Intervention

Mutations in capping protein (CP), fimbrin, and actin

Outcome

Actin filament assembly in vivo and in vitrosurrogate

Capping protein and fimbrin are important for stabilizing actin filament assembly in vivo in yeast, contrasting with previous findings in Dictyostelium.

Cite This Study

Karpova et al. (1995) studied this question.

synapsesocial.com/papers/6a7da24bcf7e8b32dacb4e45 https://doi.org/10.1083/jcb.131.6.1483

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Actin filaments in yeast are unstable in the absence of capping protein or fimbrin.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Actin filaments in yeast are unstable in the absence of capping protein or fimbrin.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider