Key result
Endovascular aneurysm repair in octogenarians with abdominal aortic aneurysms demonstrated a pooled in-hospital mortality of 5% (95% CI 3-8%) and 30-day mortality of 7% (95% CI 6-8%).
Why the study?
The study aimed to evaluate outcomes of endovascular aneurysm repair (EVAR) in octogenarians with abdominal aortic aneurysms, focusing on mortality, reintervention, and endoleaks.
What are the outcomes of endovascular aneurysm repair (EVAR) in octogenarians with abdominal aortic aneurysms?
Meta-Analysis
What are the outcomes of endovascular aneurysm repair (EVAR) in octogenarians with abdominal aortic aneurysms?
p-value: p=0.56
EVAR is a feasible and safe option for octogenarians with AAA, with low short-term mortality but a notable incidence of endoleaks and reinterventions.
Supports EVAR as feasible in octogenarians with low short-term mortality; reinforces need for vigilant surveillance due to reintervention and endoleak risks.
Objectives: This systematic review and meta-analysis aimed to evaluate the outcomes of endovascular aneurysm repair (EVAR) in octogenarians with abdominal aortic aneurysms (AAA), focusing on in-hospital mortality, 30-day mortality, reintervention rates, and the incidence of endoleaks. Data Sources: A comprehensive search was conducted in PubMed and Embase using predefined terms related to EVAR and AAA in octogenarians, without time restrictions. Study Eligibility Criteria: Included studies reported EVAR outcomes in patients aged 80 and older and provided specific data on in-hospital mortality, 30-day mortality, reintervention rates, or endoleaks. Methods: Nine studies were included after screening and data extraction. Statistical analyses were performed using R software. Pooled estimates for outcomes were calculated using a random-effects model. Heterogeneity was assessed using the Cochran Q test and I² statistic. Results: In-hospital mortality was 5% (95% CI: 3%-8%; p = 0.56; I² = 0%), and 30-day mortality was 7% (95% CI: 6%-8%; p = 0.65; I² = 0%). Reintervention rates were 6% (95% CI: 4%-10%; p < 0.01; I² = 75%). Endoleaks were reported in 23% (95% CI: 15%-33%; p < 0.01; I² = 91%), indicating significant variability. Conclusion: EVAR appears to be a feasible and safe option for octogenarians with AAA, with low in-hospital and 30-day mortality. However, the notable incidence of reinterventions and endoleaks underscores the need for careful patient selection and vigilant postoperative monitoring. Further research is required to explore long-term outcomes.
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Mahfouz et al. (2025) conducted a meta-analysis in abdominal aortic aneurysms (AAA). Endovascular aneurysm repair (EVAR) was evaluated on In-hospital mortality (95% CI 3-8, p=0.56). Endovascular aneurysm repair in octogenarians with abdominal aortic aneurysms demonstrated a pooled in-hospital mortality of 5% (95% CI 3-8%) and 30-day mortality of 7% (95% CI 6-8%).
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