Key result
Tissue Doppler derived isovolumic acceleration (IVA) was significantly lower in the subpulmonary ventricle of D-TGA patients compared to healthy controls (1.45 vs 2.31 cm/sec2; P<0.05).
Why the study?
Does tissue Doppler derived isovolumic acceleration (IVA) detect early myocardial dysfunction better than peak systolic myocardial velocity in patients after atrial repair for dextrotransposition of the great arteries?
Population
24 patients with dextrotransposition of the great arteries who underwent atrial repair in infancy, median…
Comparison
Tissue Doppler analysis of isovolumic… vs Age-matched healthy subjects
Design
Case-control
Authors
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Supports IVA for early subpulmonary dysfunction detection in D-TGA; hypothesis-generating and should not yet change practice.
Case-Control (n=36)
Does tissue Doppler derived isovolumic acceleration (IVA) detect early myocardial dysfunction better than peak systolic myocardial velocity in patients after atrial repair for dextrotransposition of the great arteries?
Absolute Event Rate: 1.45% vs 2.31%
p-value: p=<0.05
Tissue Doppler derived isovolumic acceleration is superior to peak systolic myocardial velocity for assessing a reduction in functional reserve of both ventricles in patients after atrial repair for D-TGA.
Arnold et al. (2008) conducted a case-control in Dextrotransposition of the great arteries (D-TGA) after atrial repair (n=36). D-TGA after atrial repair vs. Age-matched healthy subjects was evaluated on Isovolumic acceleration (IVA) in the subpulmonary ventricle (p=<0.05). Tissue Doppler derived isovolumic acceleration (IVA) was significantly lower in the subpulmonary ventricle of D-TGA patients compared to healthy controls (1.45 vs 2.31 cm/sec2; P<0.05).
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