Why the study?
Does propranolol reduce the rise of systolic blood pressure during human coitus?
Does propranolol reduce the rise of systolic blood pressure during human coitus?
Propranolol significantly blunts the systolic blood pressure and heart rate increases during coitus, potentially offering a safer sexual experience for patients with ischemic heart disease or hypertension.
May blunt coital hemodynamic stress in cardiac patients; leaves open prospective safety confirmation.
Summary. The ingestion of 120 to 160 mg of the β-adrenergic blocking agent, propranolol, caused a significant reduction in the rise of systolic blood pressure which occurs during human coitus. The accompanying tachycardia was also reduced. If used with caution and with careful selection of patients, the β-adrenergic blocking drugs may allow patients with ischaemic heart disease or hypertension a safer and more normal marital life, since the ease of attainment and the intensity of orgasm was not impaired.
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C. A. FOX (1970) studied this question.
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