Key result
Major clinical trials have been unable to demonstrate a clear benefit of dual-chamber over single-chamber ventricular pacing for total mortality or stroke, though it may reduce the risk of atrial fibrillation.
Design
Review
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Single-chamber pacing remains appropriate absent AF priority; leaves open targeted AF reduction benefit.
Provides an overview of the evolution and basics of cardiac pacing, including generator and lead advancements.
A 2006 study conducted a review in Bradycardia and neurally-mediated syncope. Dual-chamber pacing vs. Single-chamber ventricular pacing was evaluated. Major clinical trials have been unable to demonstrate a clear benefit of dual-chamber over single-chamber ventricular pacing for total mortality or stroke, though it may reduce the risk of atrial fibrillation.
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