Population
Canine coronary artery smooth muscle cells
Design
Preclinical
Authors
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Caution against Na-K pump mediation in coronary endothelium-dependent responses; leaves open the identity of multiple endothelium-derived inhibitory factors.
The study demonstrates that endothelium-dependent hyperpolarization and relaxation in canine coronary arteries are not mediated by the electrogenic Na-K pump, pointing to multiple endothelium-derived inhibitory factors.
Chen et al. (1989) studied this question.
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