Why the study?
Does sleep affect the duration of the Q-T interval independent of heart rate changes in patients receiving no drugs?
Population
15 patients receiving no drugs
Comparison
Sleep vs Awake state
Design
Cohort
Follow-up
3-6 days
Authors
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Requires consideration of sleep in QT assessment for arrhythmia risk; leaves open autonomic modulation of repolarization.
Does sleep affect the duration of the Q-T interval independent of heart rate changes in patients receiving no drugs?
The Q-T interval is prolonged during sleep independent of heart rate changes, likely reflecting autonomic nervous system modulation of ventricular repolarization.
Browne et al. (1983) studied this question.
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