Key result
A 6-month supervised exercise program reduced left ventricular end-diastolic diameter and improved exercise capacity compared to routine care in patients with acute myocardial infarction.
Why the study?
Does a 6-month supervised exercise programme improve ventricular remodelling and autonomic tone in patients with acute myocardial infarction and percutaneous coronary intervention?
RCT (n=60)
Single-blinded
Alternate randomization
No
Does a 6-month supervised exercise programme improve ventricular remodelling and autonomic tone in patients with acute myocardial infarction and percutaneous coronary intervention?
A 6-month supervised exercise program improves exercise capacity, autonomic tone, and prevents ventricular remodeling in post-MI patients after PCI.
Answers are grounded in this paper and cite their sources.
Supports supervised exercise post-MI with PCI; extends remodeling and capacity benefits of cardiac rehabilitation.
OBJECTIVE: To study the effects of 6 months exercise training on ventricular remodelling and autonomic tone in patients with acute myocardial infarction and percutaneous coronary intervention. DESIGN: Single-blinded randomized control trial. PARTICIPANTS: Sixty patients with acute myocardial infarction who had undergone percutaneous coronary intervention. METHODS: The exercise group followed a 6-month supervised exercise programme, while the control group received routine recommendations. All patients underwent an incremental cardiopulmonary exercise test and Doppler echocardiography at baseline and after 6 months. RESULTS: Three patients in the exercise group did not complete the programme. At 6 months follow-up, an improvement was seen in the exercise group compared with the control group regarding peak VO2 (p<0.01), Powermax (p<0.05), VO2 at anaerobic threshold (p<0.01), time to reach anaerobic threshold (p<0.05), heart rate recovery (p<0.01), left ventricular end-diastolic diameter (p<0.01) and left ventricular ejection fraction (p<0.05). CONCLUSION: Six months exercise training in patients with acute myocardial infarction and percutaneous coronary intervention with mild ventricular systolic dysfunction could prevent ventricular remodelling to a certain extent, and favourable modulating sympatho-vagal balance may be an important mechanism.
No takes yet. Share an insight, caveat, or question.
Yi et al. (2008) conducted an RCT in Acute myocardial infarction post-percutaneous coronary intervention (n=60). Supervised exercise program vs. Routine recommendations and pharmacological therapy was evaluated on Left ventricular end-diastolic diameter (LVDd) at 6 months (p=0.018). A 6-month supervised exercise program reduced left ventricular end-diastolic diameter and improved exercise capacity compared to routine care in patients with acute myocardial infarction.
Synapse has enriched 10 related papers. Consider them for comparative context: