This report of three brothers developing critical aortic stenosis provides further evidence for a genetic influence in congenital bicuspid aortic valve disease.
Supports family history assessment in bicuspid aortic valve; leaves open whether genetic testing alters management.
It has been suggested that genetic factors may play a role in the aetiology of congenital bicuspid aortic valve disease. This report describes a family in which three male siblings with bicuspid aortic valves developed critical aortic stenosis. This provides further evidence that an hereditary mechanism may play a role in some patients with this condition.
No takes yet. Share an insight, caveat, or question.
McDonald et al. (1989) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: