Population
Male Sprague-Dawley rats with and without lamina terminalis (LT) lesions
Comparison
0.9% NaCl in drinking water for 14 to 15 days vs Normal water for 14 to 15 days
Design
Preclinical
Follow-up
14 to 15 days
Authors
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Supports ventral LT mediation of salt-enhanced RVLM sympathetic responses in rats; hypothesis-generating with no immediate clinical implications.
Neurons of the ventral lamina terminalis mediate the enhanced responsiveness of RVLM sympathetic neurons induced by increased dietary salt.
Adams et al. (2009) studied this question.
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