What question did this study set out to answer?

To describe the clinical manifestations, microbiological spectrum, treatment approaches, and patient outcomes associated with implantable electrophysiologic cardiac device infections.

October 17, 2000Annals of Internal Medicine

Diagnosis and Management of Infections Involving Implantable Electrophysiologic Cardiac Devices

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Population

123 patients with infections involving implantable cardiac electrophysiologic devices at a single center in…

Design

Case_series

Authors

JCJimmy ChuaTarumanagara University

Discussion

Member takes

Implication

May support complete extraction with antibiotics for device infections; leaves open need for prospective trials to confirm outcomes.

Key Points

To describe the clinical manifestations, microbiological spectrum, treatment approaches, and patient outcomes associated with implantable electrophysiologic cardiac device infections.
Retrospective case series of N=123 patients with infections involving permanent pacemakers (n=87) or implantable cardioverter defibrillators (n=36) at The Cleveland Clinic Foundation.
Assessed demographic factors, clinical presentation, time to diagnosis, microbiological findings, surgical removal strategies, and follow-up clinical outcomes.
The most common clinical signs were pocket erythema and local pain, with coagulase-negative staphylococci (68%) and Staphylococcus aureus (23%) identified as the predominant pathogens.
Complete device extraction was achieved in 95% of patients (n=117) alongside a median 28 days of antibiotic therapy, achieving 0% operative mortality, an 8% crude mortality rate, and a 3% relapse rate.

Structured PICO

Population

123 patients with infections involving implantable cardiac electrophysiologic devices (87 with permanent pacemakers, 36 with implantable cardioverter defibrillators) at a single center in Cleveland, Ohio.

Intervention

Complete device extraction (all equipment) and antimicrobial therapy (median 28 days).

Outcome

Clinical presentation, treatment, and outcome (including operative mortality, crude mortality, and relapse rates).hard clinical

Complete device removal combined with antimicrobial therapy is a safe and effective strategy for managing infections of implantable electrophysiologic cardiac devices, with zero operative mortality and low relapse rates.

Cite This Study

Jimmy Chua (2000) studied this question.

synapsesocial.com/papers/6a7dcb1c699b737ada99a0bb https://doi.org/10.7326/0003-4819-133-8-200010170-00011

Topics

Cardiac device therapy

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Diagnosis and Management of Infections Involving Implantable Electrophysiologic Cardiac Devices

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Diagnosis and Management of Infections Involving Implantable Electrophysiologic Cardiac Devices

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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