Why the study?
Does pharmacologic prophylaxis reduce venous thromboembolism rates in patients following elective major surgery?
Population
Patients following elective major surgery
Comparison
Pharmacologic prophylaxis vs No pharmacologic prophylaxis
Design
Cohort
Authors
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No VTE reduction with prophylaxis in elective surgery cohort; should not yet change practice and leaves open need for randomized confirmation.
Does pharmacologic prophylaxis reduce venous thromboembolism rates in patients following elective major surgery?
Despite an increase in the use of pharmacologic prophylaxis between 2003/4 and 2007/8, venous thromboembolism rates were not significantly reduced among treated patients following elective major surgery.
Qadan et al. (2010) studied this question.
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