August 14, 2013PLoS ONEOpen Access

Echocardiographic Parameters in Patients with Pulmonary Arterial Hypertension: Correlations with Right Ventricular Ejection Fraction Derived from Cardiac Magnetic Resonance and Hemodynamics

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Why the study?

Do echocardiographic parameters correlate with CMR-derived right ventricular ejection fraction and hemodynamics in patients with pulmonary arterial hypertension?

Population

30 patients with pulmonary arterial hypertension, mean age 30, 80% female. Included 24 with idiopathic PAH…

Design

Cohort

Authors

TYTao YangUniversity of Science and Technology of China LYLiang YuHangzhou Normal University YZYan ZhangZhejiang Chinese Medical University

Discussion

Member takes

Implication

May enable noninvasive RV monitoring in PAH; leaves open prospective validation versus CMR.

Structured PICO

Do echocardiographic parameters correlate with CMR-derived right ventricular ejection fraction and hemodynamics in patients with pulmonary arterial hypertension?

Population

30 patients with pulmonary arterial hypertension (mPAP ≥25 mmHg and PCWP ≤15 mmHg at rest), mean age 30, 80% female. Included 24 with idiopathic PAH, 5 with connective tissue disease-associated PAH, and 1 with hereditary PAH.

Intervention

Echocardiography (measuring TAPSE, S', IVA, RVFAC, RVMPI, and RVETD/LVETD)

Outcome

Correlation between echocardiographic parameters and right ventricular ejection fraction (RVEF) derived from cardiac magnetic resonance (CMR)surrogate

Echocardiographic parameters IVA and RVETD/LVETD can independently reflect right ventricular ejection fraction regardless of hemodynamics in patients with pulmonary arterial hypertension.

Limitations

Echocardiography, CMR, and right heart catheterization were not performed simultaneously (within 1 week interval)
Small sample size did not allow evaluation of data in patients with different stages of PAH

Cite This Study

Yang et al. (2013) studied this question.

synapsesocial.com/papers/6a7dcf23cbfe537a718c90a3 https://doi.org/10.1371/journal.pone.0071276

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Echocardiographic Parameters in Patients with Pulmonary Arterial Hypertension: Correlations with Right Ventricular Ejection Fraction Derived from Cardiac Magnetic Resonance and Hemodynamics

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Echocardiographic Parameters in Patients with Pulmonary Arterial Hypertension: Correlations with Right Ventricular Ejection Fraction Derived from Cardiac Magnetic Resonance and Hemodynamics

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider