Key result
Women with significant tricuspid regurgitation had better 10-year survival than men (49% vs. 39%; p=0.001), but this difference was neutralized after propensity score matching (p=0.228).
Why the study?
Differences in etiology, comorbidities, echocardiographic parameters, and prognosis between men and women with significant tricuspid regurgitation were not well established.
Are there sex-specific differences in etiology and prognosis in patients with significant tricuspid regurgitation?
Observational (n=1,569)
Are there sex-specific differences in etiology and prognosis in patients with significant tricuspid regurgitation?
Absolute Event Rate: 49% vs 39%
p-value: p=0.001
In patients with significant tricuspid regurgitation, long-term survival is similar between men and women after adjusting for confounders, but the underlying etiology remains a significant predictor of mortality.
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Women with significant TR had better survival than men; leaves open whether sex-specific risk models improve stratification in prospective cohorts.
Dietz et al. (2021) conducted an observational in Significant tricuspid regurgitation (n=1,569). Female sex vs. Male sex was evaluated on All-cause mortality (p=0.001). Women with significant tricuspid regurgitation had better 10-year survival than men (49% vs. 39%; p=0.001), but this difference was neutralized after propensity score matching (p=0.228).
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