December 1, 1976Circulation Research

Site of myocardial infarction. A determinant of the cardiovascular changes induced in the cat by coronary occlusion.

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Why the study?

Does the site of coronary occlusion determine the hemodynamic and cardiac rhythm changes in a feline model of acute myocardial infarction?

Population

58 anesthetized cats

Comparison

Occlusion of the left anterior descending, left… vs Comparison between the three different coronary…

Design

Preclinical

Authors

PCPeter B. CorrElectrophysiology DPDavid L. PearleInterventional / Structural Cardiology JHJohn R. HintonGeorgetown University

Discussion

Member takes

Implication

Highlights occlusion-site effects in feline AMI; leaves open human translation and clinical relevance.

Structured PICO

Does the site of coronary occlusion determine the hemodynamic and cardiac rhythm changes in a feline model of acute myocardial infarction?

Population

58 anesthetized cats

Intervention

Occlusion of the left anterior descending (LAD), left circumflex, or right coronary artery

Comparator

Comparison between the three different coronary artery occlusion sites

Outcome

Changes in heart rate, blood pressure, cardiac output, total peripheral resistance (TPR), cardiac rhythm, and mortalitysurrogate

The site of experimental coronary occlusion in cats is a major determinant of the hemodynamic and cardiac rhythm changes occurring after acute myocardial infarction, which is related to the anatomical distribution of the occluded artery.

Cite This Study

Corr et al. (1976) studied this question.

synapsesocial.com/papers/6a7dd09e87be3f923b5ca55c https://doi.org/10.1161/01.res.39.6.840

Topics

Coronary CT angiography

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December 1, 1976Circulation Research

Site of myocardial infarction. A determinant of the cardiovascular changes induced in the cat by coronary occlusion.

View Full Paper

Ask AI

Bookmark

Why the study?

Does the site of coronary occlusion determine the hemodynamic and cardiac rhythm changes in a feline model of acute myocardial infarction?

Population

58 anesthetized cats

Comparison

Occlusion of the left anterior descending, left… vs Comparison between the three different coronary…

Design

Preclinical

Authors

PCPeter B. CorrElectrophysiology DPDavid L. PearleInterventional / Structural Cardiology JHJohn R. HintonGeorgetown University

Discussion

Member takes

Implication

Highlights occlusion-site effects in feline AMI; leaves open human translation and clinical relevance.

Structured PICO

Does the site of coronary occlusion determine the hemodynamic and cardiac rhythm changes in a feline model of acute myocardial infarction?

Population

58 anesthetized cats

Intervention

Occlusion of the left anterior descending (LAD), left circumflex, or right coronary artery

Comparator

Comparison between the three different coronary artery occlusion sites

Outcome

Changes in heart rate, blood pressure, cardiac output, total peripheral resistance (TPR), cardiac rhythm, and mortalitysurrogate

Cite This Study

Corr et al. (1976) studied this question.

synapsesocial.com/papers/6a7dd09e87be3f923b5ca55c https://doi.org/10.1161/01.res.39.6.840

Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

Topics

Coronary CT angiography

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