Why the study?
Heart failure with preserved ejection fraction is a poorly understood complication of diabetes mellitus, and little is known about whether exosomal microRNAs can serve as biomarkers for it.
Population
STZ-induced diabetic rats and non-diabetic controls
Comparison
STZ-induced diabetic HFpEF rats vs non-diabetic controls
Design
Animal experimental study
Authors
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May aid noninvasive HFpEF diagnosis in diabetes; leaves open human validation from rodent data.
Key points are not available for this paper at this time.
Huang et al. (2022) studied this question.
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