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December 22, 2006European Journal of Heart Failure

Characterization of Health-Related Quality of Life in Heart Failure Patients with Preserved Versus Low Ejection Fraction in CHARM

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Why the study?

Is health-related quality of life different between heart failure patients with preserved versus low ejection fraction?

Population

2,709 patients with symptomatic heart failure enrolled in the CHARM HRQL study, stratified into preserved…

Comparison

Preserved LVEF (>40%) vs Low LVEF (≤40%)

Design

Cross-sectional

Authors

ELEldrin F. LewisGeneral CardiologyGLGervasio A. LamasGeneral CardiologyEOEileen O’MearaHeart Failure & Transplant

Discussion

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Implication

HRQL is comparably impaired across LVEF strata; leaves open differential treatment effects by phenotype.

Structured PICO

Is health-related quality of life different between heart failure patients with preserved versus low ejection fraction?

P
Population
2,709 patients with symptomatic heart failure (NYHA Class II-IV) enrolled in the CHARM HRQL study, stratified into preserved LVEF (>40%) and low LVEF (≤40%)
I
Intervention
Preserved LVEF (>40%)
C
Comparator
Low LVEF (≤40%)
O
Outcome
Health-related quality of life (HRQL) assessed by the Minnesota Living with Heart Failure questionnaire at randomizationpatient reported

Health-related quality of life is equally impaired in symptomatic heart failure patients regardless of whether they have preserved or reduced ejection fraction.

Cite This Study

Lewis et al. (2006) studied this question.

synapsesocial.com/papers/6a7de8bb968fa26fcacb53bchttps://doi.org/10.1016/j.ejheart.2006.10.012

Topics

HFrEF treatmentHeart failure
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