Why the study?
Both cardiogenic shock and critical culprit lesion locations are associated with worse STEMI outcomes, but how their combination affects prognosis in Japanese patients in the PPCI-era required examination.
Does the combination of cardiogenic shock and critical culprit lesion location worsen prognosis in STEMI patients?
Population
624 Japanese STEMI patients admitted to a single hospital
Comparison
Four groups based on presence or absence of CS and CCLLs
Design
Single-centre observational cohort study
Follow-up
1 year
Authors
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Marks very high-risk STEMI phenotype; leaves open whether targeted interventions improve survival.
Does the combination of cardiogenic shock and critical culprit lesion location worsen prognosis in STEMI patients?
STEMI patients presenting with both cardiogenic shock and critical culprit lesion locations have a profoundly worse prognosis, with a 17-fold increased risk of all-cause death compared to those with neither.
Arai et al. (2022) studied this question.
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