January 14, 2009Journal of Lipid ResearchOpen Access

Plasma apolipoprotein AV levels in mice are positively associated with plasma triglyceride levels

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Population

Various mouse models including wild-type mice, glycosylphosphatidylinositol-anchored HDL binding protein…

Design

Preclinical

Authors

SVStefan F.C. VaessenPerstorp (Sweden)GDGeesje M. Dallinga‐ThieGeneral / Preventive / Lipids CRColin J.D. RossUniversity of British Columbia

Discussion

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Implication

ApoAV may mark TG hydrolysis demand in mice; hypothesis-generating for human hypertriglyceridemia studies.

Structured PICO

Population

Various mouse models including wild-type mice, glycosylphosphatidylinositol-anchored HDL binding protein 1-deficient mice, and LPL-deficient mice

Intervention

LPL gene transfer (in LPL-deficient mice)

Outcome

Correlation between plasma apolipoprotein AV (apoAV) and triglyceride (TG) levelssurrogate

In mouse models, plasma apoAV levels are positively correlated with triglyceride levels, suggesting that higher apoAV reflects an increased demand for triglyceride hydrolysis.

Cite This Study

Vaessen et al. (2009) studied this question.

synapsesocial.com/papers/6a7deec77c193befc433a56f https://doi.org/10.1194/jlr.m800551-jlr200

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Plasma apolipoprotein AV levels in mice are positively associated with plasma triglyceride levels

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Plasma apolipoprotein AV levels in mice are positively associated with plasma triglyceride levels

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider