Self-reported non-adherence to P2Y12 inhibitors in patients undergoing percutaneous coronary intervention: Application of the medication non-adherence academic research consortium classification

Figures

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  Fig 1. Patient flow. DAPT = dual antiplatelet therapy, PCI = percutaneous coronary intervention.

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  Fig 2. Overview of non-adherence according to NARC classification. NARC = non-adherence academic research consortium.

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  Fig 3. Kaplan-Meier cumulative event curve for POCE at 1 year. POCE = patient-oriented composite endpoints.

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  Fig 4. Multivariable Cox analysis for POCE at 1 year according to non-adherence levels. Of the study patients, 90.4% (3525 of 3896 patients) were included in the multivariable models. The following covariates were entered in the models: age, female sex, diabetes mellitus, eGFR, peripheral artery disease, myocardial infarction at presentation, cardiogenic shock, chronic obstructive lung disease, history of cancer, history of PCI, and use of new generation DES. CI = confidence interval, DAPT = dual antiplatelet therapy, DES = drug eluting stent, eGFR = estimated glomerular filtration rate, HR = hazard ratio, PCI = percutaneous coronary intervention.