2020 Eberhard F. Mammen Award Announcements: Part II—Young Investigator Awards

Welcome to the latest of our Eberhard F. Mammen award announcements. As noted many times previously, Thieme, the publisher of Seminars in Thrombosis and Hemostasis (STH), has created the “ Eberhard F. Mammen Excellence in Thrombosis and Hemostasis Awards ” in honor of Eberhard Mammen ([ Fig. 1 ]), and in recognition of his contribution to this field and to the journal that he both founded and steered for over three decades (see [ Table 1 ] for relevant references). These awards began in 2009, under two categories; the current award details and conditions are as follows: Table 1 Listing of relevant editorials published in STH as related to the initiation of the Eberhard F. Mammen awards, as well as previous award announcements 1. Favaloro EJ. Welcome to a special issue of Seminars in Thrombosis and Hemostasis—the closing issue for 2008. Semin Thromb Hemost 2008;34:693–696 2. Favaloro EJ. A Tribute to Eberhard F. Mammen, M.D. (1930–2008). Semin Thromb Hemost 2008;34:703–708 3. Favaloro EJ. Welcome to the first issue of Seminars in Thrombosis and Hemostasis for 2009. Semin Thromb Hemost 2009;35:1–2. 4. Favaloro EJ. Winners of the inaugural Eberhard F. Mammen Award for most popular article. Semin Thromb Hemost 2009;35:587–590 5. Favaloro EJ. 2009 Eberhard F. Mammen Young Investigator Award winners. Semin Thromb Hemost 2010;36:469–470 6. Favaloro EJ. Winners of the 2010 Eberhard F. Mammen Award for most popular article during 2008–2009. Semin Thromb Hemost 2010;36(7):685–92. 7. Favaloro EJ. 2011 Eberhard F. Mammen Award announcements. Semin Thromb Hemost 2011;37(5):431–9. 8. Favaloro EJ. 2012 Eberhard F. Mammen Award announcements. Semin Thromb Hemost 2012;38:425–32. 9. Favaloro EJ. 2013 Eberhard F. Mammen Award announcements. Semin Thromb Hemost 2013;39:567–74. 10. Favaloro EJ. 2014 Eberhard F. Mammen award announcements: Part I-most popular articles. Semin Thromb Hemost 2014;40(4):407–12. 11. Favaloro EJ. 2014 Eberhard F. Mammen Award announcements: Part II - young investigator awards. Semin Thromb Hemost 2014;40(7):718–23. 12. Favaloro EJ. 2015 Eberhard F. Mammen Award announcements: Part I-most popular articles. Semin Thromb Hemost 2015;41(7):673–9. 13. Favaloro EJ. 2015 Eberhard F. Mammen Award announcements: Part II-young investigator awards. Semin Thromb Hemost 2015;41(8):809–15. 14. Favaloro EJ. 2016 Eberhard F. Mammen Award announcements: Part I - most popular articles. Semin Thromb Hemost 2016;42(4):325–30. 15. Favaloro EJ. 2016 Eberhard F. Mammen Award announcements: Part II-young investigator awards. Semin Thromb Hemost 2017;43(3):235–241. 16. Favaloro EJ. 2017 Eberhard F. Mammen Award announcements: Part I-most popular articles. Semin Thromb Hemost 2017;43(4):357–363. 17. Favaloro EJ. 2017 Eberhard F. Mammen Award announcements: Part II- young investigator awards. Semin Thromb Hemost 2018;44(2):81–88. 18. Favaloro EJ. 2018 Eberhard F. Mammen Award announcements: Part I-most popular articles. Semin Thromb Hemost 2018;44(3):185–192. 19. Favaloro EJ. 2018 Eberhard F. Mammen Award announcements: Part II-young investigator awards. Semin Thromb Hemost 2019;45(2):123–129. 20. Favaloro EJ. 2019 Eberhard F. Mammen Award announcements: Part I-most popular articles. Semin Thromb Hemost 2019;45(3):215–224. 21. Favaloro EJ. 2019 Eberhard F. Mammen Award announcements: Part II—young investigator awards. Semin Thromb Hemost 2020;46(2):105–113 22. Favaloro EJ. 2020 Eberhard F. Mammen Award announcements: Part I-most popular articles. Semin Thromb Hemost 2020;46(4):383–392. Fig. 1 Eberhard F. Mammen (1930–2008). Most popular article awards: Awarded to the authors of the most popular articles published in STH. The awards are determined by the Editor in Chief on the basis of user statistics from Thieme e-journals from the preceding 2 years. Prefaces, errata, letters to the editor, and editorials, and previous award-winning articles, are excluded from further consideration of these awards, which currently comprise two categories: one for “Open Access” articles, and another for a “General Category.” There are two major cash prizes of US$1,000 for each category. In addition, winners of the “General Category” awards are granted “open access” status for these articles thereafter. Young investigator awards: Best presentation or meeting abstract by a young investigator—as presented or delivered to an international or large regional meeting on a topic related to the fields of thrombosis and hemostasis—and whose subject matter is determined to be in the spirit of Dr. Mammen. Up to six cash prizes of US$1,000 are given in any year. There are some additional considerations and conditions for the award, and awardees are expected to prepare a review or other papers related to the topic of their presentation (or as otherwise agreed) for publication in STH. In general, previous award winners are excluded from a second award to enable more individuals to be recognized. After nominations are received, the awardees are selected by a vote of the senior editors of STH. Any potential conflicts of interest are managed by first identifying these, and then excluding those with potential conflicts from voting. Finally, given the current COVID-19 pandemic, many international congresses have become virtual meetings, and accordingly, virtual meeting presentations can also be considered for the award. Further details of the awards and the award winners are posted online ( https://www.thieme-connect.com/products/ejournals/journal/10.1055/s-00000077 ), and previous award winner announcements are also available in print (see [ Table 1 ] for a listing of relevant editorials published in this journal as related to the initiation of the Eberhard F. Mammen awards, as well as previous award announcements; these publications are also available for free download from the journal Web site: < https://www.thieme-connect.com/products/ejournals/journal/10.1055/s-00000077 >). The winners of the 2020 Eberhard F. Mammen awards for the most popular articles from STH for the period of 2018 to 2019 inclusive were announced in an earlier issue of the journal.[ 1 ] It is therefore with great pleasure that we would like to announce the winners of the latest round of Young Investigator Awards. As mentioned above, the Young Investigator Awards represent winners of the best presentation or meeting abstract by a young investigator—as presented or delivered to an international or large regional meeting (virtual meetings permissible) on a topic related to the fields of thrombosis and hemostasis—and whose subject matter is determined to be in the spirit of Dr. Mammen. There are additional considerations given that the nominees' presentations are not always seen by all of the possible award nominators, being drawn from the editorial team of the journal. The latest winners are identified below and also in [ Table 2 ], with a running list of previous awardees, and the resulting publications in the journal, given in [ Table 3 ]. The latest awardees were derived from a variety of meetings, including the latest meetings of the International Society on Thrombosis and Haemostasis (ISTH) and the American Society of Hematology. All meetings were held virtually. Table 2 Latest (2020) Eberhard F. Mammen Young Investigator Award winners Awardee Current affiliation(s) Presentation(s) awarded Proposed submission to STH Hanny Al-Samkari Division of Hematology/Oncology, Hereditary Hemorrhagic Telangiectasia Center, Massachusetts General Hospital, Harvard Medical School, United States ISTH2020 ( https://www.isth2020.org/ ). Presentation: Thrombosis, bleeding, and the effect of anticoagulation on survival in critically ill patients with COVID-19 in the United States. Systemic angiogenic inhibition to treat bleeding in hereditary hemorrhagic telangiectasia Matthias M Engelen Center for Molecular and Vascular Biology, Department of Cardiovascular Diseases, University Hospitals (UZ) Leuven, Leuven, Belgium ISTH2020 ( https://www.isth2020.org/ ). Presentation: Incidence of venous thromboembolism in patients discharged after COVID-19 hospitalization. Venous thromboembolism in patients discharged after COVID-19 hospitalization Imre Varju, Hungary Semmelweis University, Budapest, Hungary ISTH2020 ( https://www.isth2020.org/ ). Presentation: Fibrinogen is citrullinated in venous thrombi and forms fragile clots with increased resistance to lysis NETs at the crossroad of antithrombosis and thrombolysis Ellen Driever University Medical Center Groningen, the Netherlands International Liver Congress (ILC 2020) ( https://ilc-congress.eu/programme-digital-ilc-2020/ ). Presentation: The VWF/ADAMTS13 imbalance, but not global coagulation or fibrinolysis, is associated with outcome and bleeding in patients with acute liver failure Coagulation and inflammation in critically ill liver patients. Christine Lee Platelet and Thrombosis Research Laboratory, The ANZAC Research Institute, Concord Repatriation General Hospital, NSW Australia Faculty of Medicine and Health, University of Sydney, Sydney, NSW Australia ASH2020 ( https://ash.confex.com/ash/2020/webprogram/start.html ). Presentation: Soluble platelet agonists expand the procoagulant surface in heparin-induced thrombocytopenia. Procoagulant platelets in thrombotic conditions Maria Selvadurai Australian Centre for Blood Diseases, Monash University, Victoria, Australia ASH2020 ( https://ash.confex.com/ash/2020/webprogram/start.html ). Presentation: Soluble platelet agonists expand the procoagulant surface in heparin-induced thrombocytopenia. Mechanisms of thrombosis in HIT: an update Table 3 Eberhard F. Mammen Young Investigator Award winners from previous years Awardee Year awarded Publication arising Willem M. Lijfering 2009 Lijfering WM, Flinterman LE, Vandenbroucke JP, Rosendaal FR, Cannegieter SC. Relationship between venous and arterial thrombosis: a review of the literature from a causal perspective. Semin Thromb Hemost 2011 Nov;37(8):885–96. Salley Pels 2009 Pels SG. Current therapies in primary immune thrombocytopenia. Semin Thromb Hemost 2011 Sep;37(6):621–30. Adam Cuker 2010 Cuker A. Current and emerging therapeutics for heparin-induced thrombocytopenia. Semin Thromb Hemost 2012 Feb;38(1):31–7. Giridhara Rao Jayandharan 2010 Jayandharan GR, Srivastava A, Srivastava A. Role of molecular genetics in hemophilia: from diagnosis to therapy. Semin Thromb Hemost 2012 Feb;38(1):64–78. Timea Szanto 2010 Szántó T, Joutsi-Korhonen L, Deckmyn H, Lassila R. New insights into von Willebrand disease and platelet function. Semin Thromb Hemost 2012 Feb;38(1):55–63. Birgitta Salmela 2010 Salmela B, Joutsi-Korhonen L, Armstrong E, Lassila R. Active online assessment of patients using new oral anticoagulants: bleeding risk, compliance, and coagulation analysis. Semin Thromb Hemost 2012 Feb;38(1):23–30. Pia Riittaa-Maria Siljander 2010 Aatonen M, Grönholm M, Siljander PR. Platelet-derived microvesicles: multitalented participants in intercellular communication. Semin Thromb Hemost 2012 Feb;38(1):102–13. Romaric Lacroix 2011 Lacroix R, Dignat-George F. Microparticles: new protagonists in pericellular and intravascular proteolysis. Semin Thromb Hemost 2013 Feb;39(1):33–9. Brad McEwen 2011 McEwen BJ, Morel-Kopp MC, Chen W, Tofler GH, Ward CM. Effects of omega-3 polyunsaturated fatty acids on platelet function in healthy subjects and subjects with cardiovascular disease. Semin Thromb Hemost 2013 Feb;39(1):25–32. Neil A. Goldenberg 2011 Bernard TJ, Armstrong-Wells J, Goldenberg NA. The institution-based prospective inception cohort study: design, implementation, and quality assurance in pediatric thrombosis and stroke research. Semin Thromb Hemost 2013 Feb;39(1):10–4. Vivien Chen 2011 Chen VM. Tissue factor de-encryption, thrombus formation, and thiol-disulfide exchange. Semin Thromb Hemost 2013 Feb;39(1):40–7. Joseph E. Italiano, Jr. 2011 Italiano JE Jr. Unraveling mechanisms that control platelet production. Semin Thromb Hemost 2013 Feb;39(1):15–24. Vivian Xiaoyan Du 2012/2013 Du VX, Huskens D, Maas C, Al Dieri R, de Groot PG, de Laat B. New insights into the role of erythrocytes in thrombus formation. Semin Thromb Hemost 2014 Feb;40(1):72–80. Andrew Yee 2012/2013 Yee A, Kretz CA. Von Willebrand factor: form for function. Semin Thromb Hemost 2014 Feb;40(1):17–27. Sarah O'Brien 2012/2013 O'Brien SH. Contraception-related venous thromboembolism in adolescents. Semin Thromb Hemost 2014 Feb;40(1):66–71. Veronica Flood 2012/2013 Flood VH. Perils, problems, and progress in laboratory diagnosis of von Willebrand disease. Semin Thromb Hemost 2014 Feb;40(1):41–8. Julie Tange 2012/2013 Tange JI, Grill D, Koch CD, Ybabez RJ, Krekelberg BJ, Fylling KA, Wiese CR, Baumann NA, Block DR, Karon BS, Chen D, Pruthi RK. Local verification and assignment of mean normal prothrombin time and international sensitivity index values across various instruments: recent experience and outcome from North America. Semin Thromb Hemost 2014 Feb;40(1):115–20. Kent Chapman 2012/2013 Chapman K, Yuen S. Therapy for thrombotic thrombocytopenia purpura: past, present, and future. Semin Thromb Hemost 2014 Feb;40(1):34–40. Andreas Tiede 2014 Tiede A, Werwitzke S, Scharf RE. Laboratory diagnosis of acquired hemophilia a: limitations, consequences, and challenges. Semin Thromb Hemost 2014 Oct;40(7):803–11 Wendy Lim 2014 Lim W. Thrombotic risk in the antiphospholipid syndrome. Semin Thromb Hemost 2014 Oct;40(7):741–6. Susana Nobre Fernandes 2014 Fernandes S, Carvalho M, Lopes M, Araújo F. Impact of an individualized prophylaxis approach on young adults with severe hemophilia. Semin Thromb Hemost 2014 Oct;40(7):785–9. Maria Elisa Mancuso 2014 Mancuso ME, Fasulo MR. Thrombin generation assay as a laboratory monitoring tool during by-passing therapy in patients with hemophilia and inhibitors. Semin Thromb Hemost 2016 Feb;42(1):30–5. Coen Maas 2014 Tersteeg C, Fijnheer R, Deforche L, Pasterkamp G, de Groot PG, Vanhoorelbeke K, de Maat S, Maas C. Keeping von Willebrand factor under control: alternatives for ADAMTS13. Semin Thromb Hemost 2016 Feb;42(1):9–17. Riten Kumar 2014 Kumar R, Dunn A, Carcao M. Changing Paradigm of hemophilia management: extended half-life factor concentrates and gene therapy. Semin Thromb Hemost 2016 Feb;42(1):18–29. Juraj Sokol 2015 Sokol J, Skerenova M, Jedinakova Z, Simurda T, Skornova I, Stasko J, Kubisz P. Progress in the understanding of sticky platelet syndrome. Semin Thromb Hemost 2017;43(1):8–13 Ljubica Jovanović 2015 Jovanovic L, Antonijevic N, Novakovic T, Savic N, Terzic B, Zivkovic I, Radovanovic N, Asanin M. Practical aspects of monitoring of antiplatelet therapy. Semin Thromb Hemost 2017;43(1):14–23 Lucia Stanciakova 2015 Stanciakova L, Dobrotova M, Jedinakova Z, Duraj L, Skornova I, Korinkova L, Holly P, Danko J, Stasko J, Kubisz P. Monitoring of hemostasis and management of anticoagulant thromboprophylaxis in pregnant women with increased risk of fetal loss. Semin Thromb Hemost 2016 Sep;42(6):612–21. Tina Biss 2015 Biss TT. Venous thromboembolism in children: is it preventable? Semin Thromb Hemost 2016 Sep;42(6):603–11. Tobias Fuchs 2015 Jiménez-Alcázar M, Kim N, Fuchs TA. Circulating extracellular DNA: cause or consequence of thrombosis? Semin Thromb Hemost 2017 Sep;43(6):553–561 Jonathan M. Coutinho 2015 Silvis S, Cannegieter Coutinho for venous Semin Thromb Hemost 2016 2016 S, P. in von Willebrand understanding the and Semin Thromb Hemost 2017 2016 in the of hemophilia A. Semin Thromb Hemost 2017 2016 K, K, H, S, S, S, L, D, S, L, to in with a of in to in pregnant women with antiphospholipid or Semin Thromb Hemost 2017 2016 J, J, J, G, R. Circulating as thrombosis and Semin Thromb Hemost 2018 2016 oral in disease. Semin Thromb Hemost 2018 A. 2016 2017 I, platelet function Semin Thromb Hemost 2018 2017 E, K, extracellular in arterial and venous Semin Thromb Hemost 2019 2017 R, J, thrombotic purpura: a review of diagnosis and in Semin Thromb Hemost 2020 2017 Favaloro or oral to bleeding risk a review of and Semin Thromb Hemost 2019 2017 2018 M, for the mechanisms of current and emerging Semin Thromb Hemost 2020 2018 H, as in an role and a new Semin Thromb Hemost 2019 2018 The current role of platelet function in Semin Thromb in 2018 J, Sokol J, Simurda T, L, Z, D, Dobrotova M, J, Skornova I, Z, Kubisz P, Stasko of von Willebrand current and Semin Thromb Hemost 2020 2018 T, M, I, P, J, Kubisz P, M. and on bleeding and Semin Thromb Hemost 2019 2018 Elisa 2019 E, M, M, The role of in the of Semin Thromb Hemost Ward 2019 Ward S, The of von Willebrand factor Semin Thromb Hemost in Jonathan 2019 J, L, C. and venous on that enable and assessment of the Semin Thromb Hemost 2020 2019 and to for after acute Semin Thromb Hemost 2020 21. of 2019 B, K, M. Current in the management of women with von Willebrand Semin Thromb Hemost in 2019 D, Rosendaal and the risk of venous Semin Thromb Hemost 2020 As with these awards, the current of winners a variety of at various of their awardees are on their in or are in their and over into the of their be Hanny Al-Samkari ([ Fig. 2 is an in Medicine at Harvard Medical and a investigator in the Massachusetts General Division of he on bleeding and also as the of the Hereditary Hemorrhagic Telangiectasia Center of and including therapies for bleeding in in various and various in diagnosis and of immune thrombocytopenia. currently as investigator for in these the of the COVID-19 pandemic, he has also in of bleeding, and anticoagulation in patients with has published over articles in on and international including the for the International and is the Editor for the of Fig. 2 Young Investigator Award winner Hanny Matthias Engelen ([ Fig. 3 is a at the University of After he as a in he in as a at the University Hospitals the of therapy. he on in cardiovascular as a at the University of Leuven, under the of Dr. Dr. and Dr. awarded with best by the Society of Thrombosis and Hemostasis in and has in and a presentation at international Fig. 3 Young Investigator Award winner Matthias Imre ([ Fig. is a in and a with over years of experience in the field of with a special on the of extracellular on thrombus and his and at Semmelweis University, at the of the for for United and at Harvard Medical School, and his at is a at Semmelweis University and a at New Fig. Young Investigator Award winner Imre Ellen Driever ([ Fig. is a from the University Medical Center Groningen, the is thrombosis and hemostasis in patients with liver with a on the and of thrombosis in patients. in and also a at the Department of at the Massachusetts of Fig. Young Investigator Award winner Ellen Christine Lee ([ Fig. is a under the of Vivien Chen at the ANZAC Research and University of is in with potential and that on the of patients. In under the of and Dr. at the of Medical the Australian the of the major platelet in healthy and in patients with heparin-induced thrombocytopenia. Fig. Young Investigator Award winner Christine Maria Selvadurai ([ Fig. is a recent from Monash University and a at on platelet agonists in heparin-induced thrombocytopenia at the ANZAC Research Institute, Sydney, under the of Dr. Vivien Chen and Dr. Christine in the of II in and the of these as a and by and at the Australian Centre for Blood Diseases, Monash Fig. Young Investigator Award winner Maria All award winners were to that selected to an Eberhard F. Mammen Young Investigator award, and the additional and to have and selected for an Eberhard F. Mammen Young Investigator Dr. Mammen a in our and it is for as a hemostasis investigator to an award in his I would like to many and would not have I would also like to Dr. Favaloro and the editorial team of Seminars in Thrombosis and Hemostasis for their recognition of our The of hemostasis has more and with I we the of patients with hereditary hemorrhagic and many other bleeding and thrombotic - Hanny Al-Samkari ([ Fig. 2 and to be awarded an Eberhard F. Mammen Young Investigator Award for our on venous thromboembolism in patients discharged after COVID-19 as presented at the meeting in 2020 I would like to the Editor in Dr. and the editorial of Seminars in Thrombosis and Hemostasis for this As this a team I would like to and for their in these times and the Department of Cardiovascular the Vascular this - Matthias Engelen ([ Fig. 3 to have an Eberhard F. Mammen Young Investigator this recognition has special in an that of is as as Dr. at Dr. at and Dr. at for and and at University, and for Finally, to the for consideration and this - Imre ([ Fig. to be awarded an Eberhard F. Mammen Young Investigator I the recognition for on the between bleeding or outcome and the in patients with acute liver award a team and this would not have possible the of the in award - Ellen Driever ([ Fig. and to an Eberhard F. Mammen Young Investigator Award for our on procoagulant platelets in heparin-induced thrombocytopenia. award is a to the and I from and Vivien and and is a recognition of the team by and As a this award on to contribution in this - Christine Lee ([ Fig. is an honor to be awarded a 2020 Eberhard F. Mammen Young Investigator Award with Dr. Christine I have by a of previous winners of this award, and it is a to in their I would like to the editorial team of Seminars in Thrombosis and Haemostasis for our presentation for this award, and Dr. Favaloro for the I also to Dr. Vivien Chen and Dr. Lee for the to on this with and for their and Finally, I would like to the and of the Platelet and Thrombosis Laboratory at the ANZAC Research Institute, whose over many years this would not have - Maria Selvadurai ([ Fig. In with previous editorials, I have the Young Investigator awardees from previous years as well as the outcome of their to as in [ Table 3 ]. The most recent are also in the 2 ] [ 3 ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] [ ] I mentioned that most of the papers from earlier years have in further some of these papers or the young have one of the most popular awards. It is also to that of the Young Investigator awardees were on other to STH that were also in these most popular I to the of the current and Young Investigator Award winners to to The also that are for Young Investigator awardees, and I all awardees the best of to the by earlier award winners. Publication published All Thieme Medical New