Why the study?
To compare free-breathing stress cardiac MRI examinations using compressed sensing and motion correction with the reference standard breath-holding examination.
Does free-breathing adenosine stress cardiac MRI using compressed sensing and motion correction provide comparable image quality and functional parameters to standard breath-holding examination in patients undergoing stress cardiac MRI?
Does free-breathing adenosine stress cardiac MRI using compressed sensing and motion correction provide comparable image quality and functional parameters to standard breath-holding examination in patients undergoing stress cardiac MRI?
Free-breathing adenosine stress cardiac MRI using compressed sensing significantly reduces scan time while providing comparable diagnostic image quality and functional assessment to standard breath-holding techniques.
Answers are grounded in this paper and cite their sources.
May shorten stress CMR exams in practice; leaves open randomized confirmation of equivalence.
PURPOSE: To compare free-breathing (FB) stress cardiac MRI examinations with the reference standard breath-holding (BH) examination. MATERIALS AND METHODS: A total of 40 consecutive patients were enrolled prospectively and were examined with 3-T MRI. Functional imaging, perfusion, and late gadolinium enhancement (LGE) sequences were performed in BH and FB by using compressed sensing and in-line motion correction. Left ventricle (LV) and right ventricle (RV) functional parameters in BH and FB examinations were compared by using Bland-Altman plots and linear mixed models. Subjective image quality was assessed with a five-point scale (1 = nondiagnostic, 5 = very good). For perfusion and LGE imaging, diagnostic confidence was rated with a three-point scale (1 = low, 3 = high), and image quality was rated with a five-point scale (1 = nondiagnostic, 5 = very good). The Wilcoxon test was used to compare image quality and diagnostic confidence. Scanning time was 218 seconds (range, 130-385 seconds) for cine BH and 16 seconds (range, 11-27 seconds) for cine FB. Extent of perfusion defects, LGE, and diagnostic confidence was comparable between groups. Scanning time was 371 seconds (range, 239-502 seconds) for the LGE BH sequence and 189 seconds (range, 122-286 seconds) for the LGE FB sequence. CONCLUSION: FB adenosine stress cardiac MRI delivers diagnostic image quality and could represent an alternative for use in patients who are unable to meet the demands of multiple BHs and long examination times.
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Treutlein et al. (2019) studied this question.
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