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April 17, 2003BMJOpen Access

Hypertensive diseases of pregnancy and risk of hypertension and stroke in later life: results from cohort study

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Why the study?

Does a history of hypertensive diseases of pregnancy increase the risk of hypertension and stroke in later life?

Population

3,593 women who delivered a first, live singleton pregnancy from 1951 to 1970 in Aberdeen, Scotland. Mean…

Comparison

History of hypertensive diseases of pregnancy vs Matched women with no history of raised blood…

Design

Cohort, Nurses conducting clinical examinations were blind to study group status

Follow-up

Approximately 35 years

Authors

BWBrenda J. WilsonAlberta Health Services

Discussion

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Implication

May warrant enhanced postpartum BP surveillance in affected women; leaves open whether targeted interventions reduce long-term stroke mortality.

Structured PICO

Does a history of hypertensive diseases of pregnancy increase the risk of hypertension and stroke in later life?

P
Population
3,593 women who delivered a first, live singleton pregnancy from 1951 to 1970 in Aberdeen, Scotland. Mean age at delivery 24.2 years. Excluded: women with chronic hypertension.
I
Intervention
History of hypertensive diseases of pregnancy (gestational hypertension or pre-eclampsia/eclampsia)
C
Comparator
Matched women with no history of raised blood pressure during their first singleton pregnancy (matched for age and year of delivery)
O
Outcome
Current vital and cardiovascular health status (including hypertension, stroke, ischaemic heart disease, and mortality) ascertained through postal questionnaire, clinical examination, hospital discharge linkage, and mortality datahard clinical

Women who experience hypertensive diseases during their first pregnancy have a significantly increased long-term risk of developing hypertension and dying from stroke.

Limitations

  • Smoking data at the time of pregnancy were incomplete
  • Success of the tracing differed across the three comparison groups
  • Respondents were more likely to be in manual social classes at baseline than the starting cohort

Cite This Study

Brenda J. Wilson (2003) studied this question.

synapsesocial.com/papers/6a7e1fcf618ffb46baa2a295https://doi.org/10.1136/bmj.326.7394.845

Topics

Hypertension management
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiovascular sequelae of toxaemia of pregnancy.1997 · 255 citations
  2. 2National High Blood Pressure Education Program Working Group report on hypertension in diabetes.1994 · 1,005 citations
  3. 3How Well They Remember1995 · 259 citations
  4. 4Concomitants of Excess Coronary Deaths — Major Risk Factor and Lifestyle Findings from 10,359 Men and Women in the Scottish Heart Health Study1989 · 110 citations