Why the study?
Does aspirin therapy reduce all-cause mortality in critically ill patients?
Population
763 critically ill patients enrolled in two randomized controlled trials
Comparison
Aspirin therapy during intensive care unit stay vs No aspirin therapy during ICU stay
Design
Cohort
Follow-up
Until hospital discharge
Authors
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Aspirin was not associated with reduced ICU or hospital mortality in critically ill patients; leaves open its net effects and supports randomized trials before any practice change.
Does aspirin therapy reduce all-cause mortality in critically ill patients?
Aspirin use in critically ill patients does not reduce mortality and is associated with increased morbidity, including a higher risk of severe sepsis and prolonged ICU stay.
Harbi et al. (2016) studied this question.
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