High sensitivity Troponin I can be falsely elevated by several folds in non-cardiac conditions such as H1N1 influenza, emphasizing the need for clinical correlation.
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Requires clinical correlation for troponin in H1N1; case report leaves open antiviral effects on levels.
An adult male admitted in emergency with complaint of fever and respiratory distress. On work up several fold increase in Troponin I levels were noted. The cardiac work up did not reveal any abnormality. The patient was tested for H1N1 Influenza RNA PCR which came positive and patient was treated with Tamiflu. The spurious high sensitivity Troponin I levels assay mandates that the test result should always be seen in light of clinical scenario as non-cardiac elevations are more frequent as thought.
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Rateesh Sareen (2023) studied this question.
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