Structural Perspectives of Phospholamban, a Helical Transmembrane Pentamer
Population
Phospholamban protein in sarcoplasmic reticulum membranes
Design
Review
Authors
Discussion
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Member takes
Implication
Hypothesis-generating for phospholamban-targeted therapies in heart failure; leaves open clinical translation pending functional validation.
Structured PICO
P
Population
Phospholamban protein in sarcoplasmic reticulum membranes
This review summarizes the structural properties and functional roles of phospholamban, a key regulatory protein in cardiac calcium handling.
Cite This Study
Arkin et al. (1997) studied this question.