Population
Phospholamban protein and a 28 residue peptide including the transmembrane domain, reconstituted into…
Comparison
Phosphorylation vs Unphosphorylated state
Design
Preclinical
Authors
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Structural model of phospholamban may refine cardiac Ca2+ regulation hypotheses; leaves open functional validation in intact systems.
The study proposes a structural model for the phospholamban pentameric complex, suggesting a mechanism for Ca2+ regulation across membranes in cardiac muscle cells.
Arkin et al. (1995) studied this question.
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