Molecular dynamics simulations reveal that phospholamban undergoes large amplitude collective motions and conformational changes in lipid bilayers that likely facilitate its interaction with calcium ATPase.
No takes yet. Share an insight, caveat, or question.
Lipid bilayer promotes extended PLN conformations that may facilitate SERCA interaction; hypothesis-generating and should not yet change practice.
Houndonougbo et al. (2005) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: