Why the study?
Does arterial delivery of skeletal myoblasts result in engraftment and phenotypic modification in the murine heart?
Population
Murine heart model
Design
Preclinical
Follow-up
up to 4 months
Authors
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Arterial myoblast delivery is feasible in mice; leaves open translation to functional myocardial repair in larger models or humans.
Does arterial delivery of skeletal myoblasts result in engraftment and phenotypic modification in the murine heart?
Arterial delivery of skeletal myoblasts to the murine heart leads to long-term engraftment and phenotypic changes, suggesting potential for myocardial repair.
Robinson et al. (1996) studied this question.
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