Population
Adult cat hindlimb muscles (tibialis anterior)
Comparison
Spinal cord isolation via complete spinal cord… vs Control cats
Design
Preclinical
Follow-up
6 months
Authors
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Activity-independent mechanisms may sustain muscle enzyme coordination in disuse; leaves open human translation and clinical relevance.
Activity-independent mechanisms remain important sources of the control of skeletal muscle fiber phenotype establishment in the near absence of activity.
Roy et al. (2008) studied this question.
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