Why the study?
Does baseline myocardial blood flow and glucose uptake predict reversible ischemic dysfunction in patients with chronic anterior wall dysfunction undergoing coronary revascularization?
Population
39 patients with chronic anterior wall dysfunction and a previous infarction undergoing coronary…
Design
Cohort
Follow-up
5 months
Authors
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Challenges notion of permanent flow reduction in hibernating myocardium; extends viability concepts but leaves prospective validation open.
Does baseline myocardial blood flow and glucose uptake predict reversible ischemic dysfunction in patients with chronic anterior wall dysfunction undergoing coronary revascularization?
Chronic reversible ischemic dysfunction (hibernating myocardium) is associated with almost normal resting myocardial perfusion and maintained FDG uptake, indicating it is not caused by a permanent reduction in resting blood flow.
Gerber et al. (1996) studied this question.
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